Self‐reported changes in the expanded disability status scale score in patients with multiple sclerosis after autologous stem cell transplants: real‐world data from a single center. (2019)

 

Description: The study’s primary co‐end‐points were the recovery of granulocyte and platelet counts and transplant related mortality (TRM). Secondary endpoints were overall survival (OS) and clinical response (improvement or stabilization of the self‐reported EDSS score).

Outcomes: The overall response rate (RR) at 12 months post HSCT varies in accordance with the type of MS: 83% in RRMS, 78% in PPMS and 73% in SPMS. (RR = improvement + stabilization)